Novel POLE mutations identified in patients with IMAGE-I syndrome cause aberrant subcellular localisation and protein degradation in the nucleus | Journal of Medical Genetics
Genes | Free Full-Text | Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity
Cancer test kit - Droplex POLE - Gencurix - for genetic mutations / for genes
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations | Scientific Reports
Cancers | Free Full-Text | Polymerase Epsilon-Associated Ultramutagenesis in Cancer
Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability | PLOS ONE
Frontiers | Protumorigenic Role of Elevated Levels of DNA Polymerase Epsilon Predicts an Immune-Suppressive Microenvironment in Clear Cell Renal Cell Carcinoma
DNA polymerase mutations as drivers of genome instability and cancer
POLE Gene - GeneCards | DPOE1 Protein | DPOE1 Antibody
Pathogenic, somatic POLE mutations in precursors of endometrial and... | Download Scientific Diagram
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair | eLife
POLE, POLD1, and NTHL1: the last but not the least hereditary cancer-predisposing genes | Oncogene
DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency - ScienceDirect
Novel POLE mutations identified in patients with IMAGE-I syndrome cause aberrant subcellular localisation and protein degradation in the nucleus | Journal of Medical Genetics
Mutations in the POLE exonuclease domain in ECs. (A) Mutations in the... | Download Scientific Diagram
Role of POLE and POLD1 in familial cancer | Genetics in Medicine
Cancer Cell Metabolism Database ~~ Bioinformatics and Systems Medicine Laboratory ~~
POLE exonuclease mutations in endometrial cancer affect conserved... | Download Scientific Diagram
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status - ScienceDirect
Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population | Scientific Reports
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text
ESMO Virtual Congress 2020: High Activity of Nivolumab in Patients with Pathogenic Exonucleasic Domain POLE (edPOLE) Mutated Mismatch Repair Proficient Advanced Tumours
Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers | JCO Precision Oncology
SciELO - Brasil - First description of ultramutated endometrial cancer caused by germline loss-of-function and somatic exonuclease domain mutations in <i>POLE</i> gene First description of ultramutated endometrial cancer caused by germline loss-of-function
DNA polymerase mutations as drivers of genome instability and cancer
Mutation analysis of POLE gene in patients with early-onset colorectal cancer revealed a rare silent variant within the endonuclease domain with potential effect on splicing | SpringerLink
