High mutational burden in colorectal carcinomas with monoallelic POLE mutations: absence of allelic loss and gene promoter methylation | Modern Pathology
Ultra‐mutated colorectal cancer patients with POLE driver mutations exhibit distinct clinical patterns - Hu - 2021 - Cancer Medicine - Wiley Online Library
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text
Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers | JCO Precision Oncology
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair | eLife
![PDF] DNA Polymerase ɛ Deficiency Leading to an Ultramutator Phenotype: A Novel Clinically Relevant Entity | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/461ebce1ac0f956984d1002a47021fc49e644fac/4-Figure2-1.png "PDF] DNA Polymerase ɛ Deficiency Leading to an Ultramutator Phenotype: A Novel Clinically Relevant Entity | Semantic Scholar")
PDF] DNA Polymerase ɛ Deficiency Leading to an Ultramutator Phenotype: A Novel Clinically Relevant Entity | Semantic Scholar
Genes | Free Full-Text | Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity
Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability | PLOS ONE
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text
Mutations in the POLE exonuclease domain in ECs. (A) Mutations in the... | Download Scientific Diagram
Unusual suspects in hereditary melanoma: POT1, POLE, BAP1: Trends in Genetics
Distinct mutational profile and immune microenvironment in microsatellite-unstable and POLE-mutated tumors | Journal for ImmunoTherapy of Cancer
Increased DNA Polymerase Epsilon Catalytic Subunit Expression Predicts Tumor Progression and Modulates Tumor Microenvironment of Hepatocellular Carcinoma
A mutation in POLE predisposing to a multi-tumour phenotype
POLE Mutations and Endometrial Cancer | Castrillon Lab | UT Southwestern, Dallas, Texas
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer | PLOS Genetics
Clinicopathological and molecular characterization of high-grade endometrial carcinoma with POLE mutation: a single center study
POLE proofreading mutation, immune response and prognosis in endometrial cancer. - Abstract - Europe PMC
POLE/POLD1 mutation and tumor immunotherapy | Journal of Experimental & Clinical Cancer Research | Full Text
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations | Scientific Reports
Journal of Gynecologic Oncology
Pathogenic, somatic POLE mutations in precursors of endometrial and... | Download Scientific Diagram
Cancers | Free Full-Text | Polymerase Epsilon-Associated Ultramutagenesis in Cancer
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status - ScienceDirect
Novel POLE mutations identified in patients with IMAGE-I syndrome cause aberrant subcellular localisation and protein degradation in the nucleus | Journal of Medical Genetics
Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population | Scientific Reports
The structure of POLE and POLD1 demonstrating the position of key... | Download Scientific Diagram
